Chapter 197:
Uchiha Fugaku and Uchiha Mikoto.
In Orochimaru's mind, if those two would eventually become husband and wife, then they must have had some connection when they were young.
Just like Konoha's original twelve heroes.
Sasuke and Sakura, Naruto and Hinata—they'd known each other since childhood.
But thinking more carefully, it made sense that Fugaku and Mikoto weren't familiar with each other.
They were four or five years apart in age.
Their schooling levels were different, and their combat abilities weren't on the same level either.
And since both were from the Uchiha clan, they usually wouldn't end up in the same team!
Adding to that, it was the middle of the Second Great Ninja War, and everyone was preoccupied with battle. So... it was normal for them not to have the time to know each other.